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Depression can be triggered or worsened by life's difficulties. Paxil should be taken once a day, either in the morning or evening, with or without food. As often as several times a week or even per day, causing significant distress. Your thinking or reactions. Do not take Paxil without first talking to your doctor if you experience headache nervousness, or anxiety nausea, diarrhea, or changes in appetite or weight. Research has shown that depression and anxiety disorders usually require long-term treatment because of their chronic nature and the risk of relapse.

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